Andrew Truman, Ph.D.

CBES Area of Interest:

My laboratory focuses on the role of molecular chaperones Hsp70 and Hsp90 in cancer. We are particularly interested in understanding how phosphorylation of chaperones modulates their global interactomes and their in vivo function in cells. We believe by targeting particular phosphorylation sites, we may be able to sensitize cancer cells to a range of anticancer therapeutics.

CBES Area of Expertise:

Breast cancer; Prostate cancer; Protein-protein interactions; Mass spectrometry; CRISPR-CAS9; Post-translational modifications; Cell cycle; DNA damage response